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Increased brown iris pigmentation has occurred when the same formulation of bimatoprost ophthalmic solution was instilled directly into the eye to treat elevated intraocular pressure. Although iris pigmentation was not reported in clinical studies with LATISSE^®, patients should be advised about the potential for increased brown iris pigmentation which is likely permanent.

LATISSE^® solution is applied topically, along the skin of the upper eyelashes. It is not intended for use in the eyes, but if some solution gets into your eye, you do not need to rinse it. See the full instructions in How to Apply, and apply as instructed by your doctor.

No. LATISSE^® works gradually over the 16-week treatment period. Use of LATISSE^® more than once a day will not increase the growth of eyelashes. Please follow the directions, as instructed by your doctor.

LATISSE^® received its FDA approval in December 2008, after a team of 16 experienced doctors from all over the country conducted clinical studies. LATISSE^® is from Allergan, a specialty pharmaceutical company. Approximately 1.5 million kits of LATISSE^® have been sold.

Skin hyperpigmention (or skin darkening) is a less common side effect, which typically occurs close to where the solution is applied on the skin. This is due to an increase of melanin in the skin. The pigmentation is expected to increase as long as bimatoprost is administered, but has been reported to be reversible in most patients upon discontinuation of bimatoprost.

LATISSE^® is an ophthalmic solution. If any solution gets into the eye, it is not expected to cause harm. You do not need to rinse your eyes. LATISSE^® is not an eye drop. DO NOT APPLY in your eye or to the lower lid.

LATISSE^® is the first and only FDA-approved prescription treatment for inadequate or not enough lashes, growing them longer, fuller and darker.

No. LATISSE^® does not work in place of mascara. LATISSE^® is a solution treatment for inadequate or not enough lashes and requires a prescription from a doctor. However, mascara can be used on your eyelashes in addition to LATISSE^®.

To achieve the full effect of LATISSE^® — longer, fuller, darker lashes — you will need to use the product daily for 16 weeks. After that point, you should talk to your doctor about ongoing use.

If you stop using LATISSE^®, your eyelashes are expected to return to their previous appearance over several weeks to months.

In the long run, varicose veins may have serious consequences for the blood circulation in your venous system, such as venous stasis. Over time, venous stasis can lead to changes in your skin (redness, brown spots) which in turn could lead to a venous ulcer. The earlier varicose veins are treated (there are various treatment options), the greater will be the chance for your venous network to regenerate itself. Compression stockings should also be worn to help your venous system overcome the high venous pressure due to venous stasis.